Radiesse Facial Filler
As we age, the loss of facial volume is one of the most visible signs of aging — flatter cheeks, deepening folds along the lower face, hollowing along the jawline, and the gradual emergence of marionette lines and prejowl sulcus. Radiesse offers a uniquely effective approach to this category of aging. Unlike hyaluronic acid fillers, which add temporary volume through a gel substance, Radiesse is a biostimulatory filler — it both restores volume immediately and stimulates the body’s own collagen production over the months that follow, producing results that often last 12 to 18 months or more. Manufactured by Merz Aesthetics, Radiesse is composed of calcium hydroxylapatite (CaHA) microspheres — the same biocompatible mineral component found naturally in human bone — suspended in a gel carrier. Radiesse is one of several injectables and fillers offered at Dr. Khosh’s Manhattan practice.
Radiesse is placed at deeper tissue planes than most hyaluronic acid fillers, and getting that placement right matters. Dr. Maurice Khosh brings the kind of deep-tissue surgical anatomy expertise this requires. Dual board-certified by the American Board of Facial Plastic and Reconstructive Surgery and the American Board of Otolaryngology–Head and Neck Surgery, Dr. Khosh is a Fellow of the American College of Surgeons (FACS) and a Clinical Assistant Professor at Columbia University. He holds active hospital privileges at NewYork-Presbyterian, Mount Sinai West, the Manhattan Eye, Ear, and Throat Infirmary (MEETH), and Lenox Hill Hospital — the institutional credentialing that reflects ongoing peer review of his surgical practice. With three decades of operating in the same midface and lower-face tissue planes that Radiesse engages, Dr. Khosh brings surgical-level precision to every injection. He is a perennial Castle Connolly Top Doctor, a Super Doctors New York Rising Star, and a Patients’ Choice Award recipient.

What Radiesse Best Addresses
Radiesse is most effective for treating volume loss and contour refinement in the mid-to-lower face, where its biostimulatory effect produces both immediate and long-term improvement. Dr. Khosh uses Radiesse to address a range of aesthetic concerns where deep-tissue, collagen-stimulating volume is the right approach:
- Nasolabial Folds: The deep “parenthesis” lines that extend from the corners of the nose to the corners of the mouth
- Marionette Lines: The downturning folds from the corners of the mouth toward the chin
- Midface and Cheek Volume: Restoring lost cheek volume and re-elevating the midface contour
- Jawline Definition: Sharpening the lower-face profile with deep-plane volume restoration
- Prejowl Sulcus: Filling the depression in front of developing jowls to smooth the jawline contour
- Hand Rejuvenation: FDA-approved for restoring volume to the back of the hands
- Chin Refinement: Subtle, non-surgical enhancement of chin projection and shape
How Radiesse Differs from Other Fillers
While hyaluronic acid fillers (such as Juvederm and Restylane) add volume by holding water within a gel matrix, Radiesse works through a different mechanism: the calcium hydroxylapatite microspheres act as a scaffold that stimulates the body’s own collagen production. The immediate volume restoration is similar to HA fillers, but the long-term effect builds gradually as new collagen forms around the microspheres. Results typically last 12 to 18 months — longer than most hyaluronic acid fillers — though Radiesse is not reversible the way HA fillers are. For this reason, Radiesse is generally not used in the lips or in very superficial tissue zones where lumps or visibility would be a concern. Choosing between Radiesse and an HA filler depends on the area being treated, the depth of placement needed, and the patient’s preference for immediate adjustability versus longer duration.
“Radiesse and hyaluronic acid fillers are different tools for different problems. HA fillers are ideal where flexibility and reversibility matter; Radiesse is ideal where deep-tissue volume and collagen stimulation matter. Knowing which to choose — and when — is what determines whether the result lasts a year and looks natural, or settles in a way the patient didn’t expect.” — Dr. Maurice Khosh
Schedule Your Consultation in Manhattan
Radiesse may be the right choice for patients seeking long-lasting volume restoration in the midface, jawline, or hands. The right result depends on accurate evaluation of where volume has been lost, the appropriate depth of placement, and an honest conversation about which filler best matches your goals. To schedule a consultation at Dr. Khosh’s Park Avenue office in New York City, call (212) 339-9988 or contact us online to request an appointment.






